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Category: Autoimmune Diseases

Ulcerative colitis

Ulcerative colitis

Ulcerative colitis (UC), like Crohn's disease, is a chronic condition in which our immune cells target cells of our digestive tract. Unlike Crohn’s which affects the entire digestive tract (mouth to anus), UC begins in the rectum (connecting segment of the large intestine to the anus) and may affect the entire colon (large intestine). UC affects 0.005-0.5% of individuals per year.

Crohn's disease

Crohn's disease

Crohn's also known as regional enteritis, presents as an inflammatory bowel disease (IBD) resulting in chronic inflammation from mouth to anus. The disease progresses in "patches" meaning the areas of inflammation aren't continuous. Crohn's affects approximately 0.1-0.3% of the population. The exact cause of the illness is unknown, but several factors such as heredity and immune activation by a bacterium or virus have been proposed in the development of IBD.

Celiac disease

Celiac disease

Celiac disease is known by many names such as gluten sensitivity enteropathy, celiac sprue, and nontropical sprue. This chronic illness presents as an auto-immune reaction in which our immune cells attack tissues of the small intestine when we consume gluten thus, resulting in poor nutrient absorption. Worldwide prevalence based on blood tests is 1.4% while 0.7% is based on biopsy. The disease has been associated with heredity, certain genetic mutations predispose patients to develop the illness.